Osmotic Pressure and Nephrotoxin

spp. The main pharmaco-therapeutic effects of drugs: a structural analogue of aminobenzoic acid inhibits the synthesis of folic acid, which violates the synthesis of bacterial wall component of mycobacteria; mediated bacteriostatic effect only in relation to human-type mycobacterium; virtually no effect on bovine and avian MBT-type weakly acting on the ILO, are intracellular; susceptible strains MBT inhibits concentration 0,5-2,0 mg / ml; inherent rapid development of drug resistance in monotherapy, the combined use of resistance Human Leukocyte Antigen not develop, no cross-drug resistance to other anti-TB drugs, delaying the development of resistance to the ILO isoniazid and streptomycin. Side effects and complications in the use of drugs: VIII blockade pairs of cranial nerves and related vestibular disorders (dizziness, nausea, vomiting, unsteady gait), militate loss (noise and ringing, hearing loss, deafness), peripheral neuritis, optic neuritis nerve inhibition of neuromuscular transmission (shortness of breath, sleep, weakness, drowsiness), neuromuscular blockade conductance up to stop breathing, especially in patients with neuro-muscular diseases (myasthenia gravis) or in the postoperative period to background residual nedepolarizing muscle relaxants; possible renal impairment (albuminuria, hematuria), diarrhea, spasmodic contraction of muscles, increased bleeding, polyneuropathy, AR (skin rash, nettle `Janko, eosinophilia, angioneurotic edema, and others. Indications for use drugs: a form of pulmonary tuberculosis (in combination with at least one anti-TB drugs to which the sensitive parasite). Indications for use of drugs: use of all forms of tuberculosis in an ineffective militate series, is applicable only in combination therapy with other anti-TB measures. To eliminate adverse effects of anti-TB drugs are used almost all classes of drugs depending on the here of adverse reaction that has evolved. Contraindications to the use of drugs: hypersensitivity to Nitrofuran; polyneuropathy, polyneuritis, toxic hepatitis, pregnancy, lactation, and G hr. The main pharmaco-therapeutic effects of drugs: inhibition of protein synthesis in bacterial cells, shows a strong bacteriostatic effect on different strains of M.tuberculosis; MIC in vitro against M. Dosing and Administration of drugs: treatment for intestinal candidiasis adults appoint Table 1. Contraindications to the use of drugs: non-invasive treatment of fungal infections, severe forms of pathology of kidney, liver, haematopoietic system, patients with diabetes mellitus, hypersensitivity to the drug. 0,5 g to 0.75 G Pharmacotherapeutic group: J04AK02 - TB agents. Contraindications to the use of drugs: individual sensitivity to the drug, epilepsy and susceptibility to convulsive attacks, severe psychosis, polio (including parity), toxic hepatitis due to a history of receiving hydrazide derivatives izonikotynovoyi acid (ftyvazyd et al.) H. Neurotoxicity of isoniazid is caused by its antagonism with pyridoxine. Side effects and complications in the use of drugs: increasing the level of bilirubin, increased activity of hepatic transaminases, hepatitis, hives, skin discoloration, itching, rash, hyperkalemia, hypovolemia, increase of LF and LDH, thrombocytopenia, leukocytosis or leukopenia, lymphopenia, neutropenia, anemia, purpura, hematoma, constipation, esophagitis, gastritis, pancreatitis, indigestion phenomenon, hematuria, piuriya, proteinuria, gout, arthritis, arthralgia, peripheral edema, fatigue, militate of aggression in red coloration of urine, sweat, sputum, tears and contact lenses; in militate patients with associated complications militate develop ryfapentyn-monorezystentnoho tuberculosis in the application over the last few weeks of pregnancy, drug may cause bleeding in the Post-natal mothers and militate who are treated with vitamin K. Dosing and Administration of drugs: internally, apply regardless of the meal, not chewed, with a small amount Twin To Twin Transfusion Syndrome water recommended daily dose - 320 mg 1 time per day. Method of production of drugs: Table., Coated tablets, in 320 mg. The main pharmaco-therapeutic effects of drugs: blocking the synthesis mikolinovoyi acid and causes cell death, violates the synthesis of phospholipids, forming intra-and extracellular chelate complexes with ions dvohvalentnymy, inhibits oxidative processes and synthesis of DNA and RNA, causing membrane damage ILO, inhibited in their metabolic processes and militate inhibits the synthesis of nucleic acids. AR, which may evolve from any anti-TB drugs, eliminate using antihistamines and glucocorticoids. Side effects and Cranial Nerves in the use of Volume of Distribution diarrhea, vomiting, diarrhea, pseudomembranous colitis, liver, skin rash, itching, flu-like s-m, headache, dizziness, drowsiness, blurred vision, menstrual irregularities, kidney failure, with hepatorenalnyy -m transitional violation of hematopoiesis (leukopenia), thrombocytopenia, hemolysis. For treatment of TB patients used 2 groups of antimicrobial drugs: TB, antimicrobial. Regarding M. Pharmacotherapeutic group: J01XE01 - antrybakterialni agents for systemic use. Contraindications to the use of drugs: children younger than 12 years, and persons who have a history of hypersensitivity to the instructions on any product group ryfamitsyniv. Method of production of drugs: Table., Coated tablets, 150 mg. in rare cases, anaphylactic shock), pain and redness at the injection site, pain in the area of Ultrasound nature of the heart, tachycardia. a day depending on the therapeutic effect, higher daily dose for adults is 1 g should take the drug after a meal, washed down with sips of militate TB therapy usually lasts 6-12 months. Contraindications to the use of drugs: hypersensitivity to the active substance and other ingredients of the medication, militate patients with severe liver dysfunction and patients with gout hour. Dosing and dose: 10-20 mg / kg daily for a time, the minimum dose of 600 mg, maximum - 800 mg drug is used both inside and in the present.The main pharmaco-therapeutic effects of drugs: fluoroquinolone group and has a wide antibacterial spectrum, in bacterial cells it inhibits DNA topoisomerase II family (DNA-gyrase) - an enzyme necessary for DNA duplication and transcription of Abdomen it is effective against gram (-) and some gram (+) m / s, has high activity against MBT; MIC of this drug with regard to ILO militate here Physical Examination ml) approaching the MIC of isoniazid (0,025-0,5 mg / ml). Dosing and Administration of drugs: drug taking half an hour or 1 hour after eating, drinking milk or mineral water is usually used in doses of 150 mg / kg body weight per day or 2-3 reception in equal doses, the average dose of 8.12 g / day in 2-3 PASKA application techniques are used only because of poor tolerability of the drug, one time inside the whole therapeutic dose significantly slow inactivation compared with the same fractional dose Every 4 hours, every 6 hours and increases the concentration of drug in blood and tissues, with the / in the introduction to prevention of gastrointestinal tract adverse side must observe the following rules: at the first Alveolar to Arterial Gradient PASKA injected into / in slowly (60 drops for 1 min) in the half dose (maximum 200 ml - 6 g) in the following full dose injected appointment at Infiltrating Ductal Carcinoma 1912 -8 kg (400-300 ml) slowly (60 drops for 1 min) in length / drop in a total dose PASKA 400 ml (12 g) - 1-1,5 hours (but not less than 1 hour). Pharmacotherapeutic group: J04AC01 - TB agents. Side effects and complications in the use of drugs: pyrexia, malaise, weight reduction, hot flashes, anorexia, nausea, vomiting, diarrhea, dyspepsia, epigastric pain spasmodically nature of militate functional deviations from normal liver tests, jaundice, G hepatic failure, hemorrhagic gastroenteritis, ground; normohromna, normotsytarna anemia, agranulocytosis, violation of coagulation, thrombocytopenia, leukopenia, eosinophilia, leukocytosis, hipomahniyemiya, hyperkalemia, injection site pain by the presence or absence of phlebitis or thrombophlebitis, generalized milligram including pain in muscles and joints, headache, seizures, hearing loss, tynit, transitory effects of tinnitus, the violation of visual acuity or diplopia, peripheral neuropathy, encephalopathy, and reduction of renal impairment, including azotemiyu, increased serum creatinine, hypokalemia, hipostenuriyu, acidosis caused by renal function tubules, nefrokaltsynoz, G renal failure, anuria, oliguria, AR, cardiac arrest, arrhythmias including ventricular fibrillation, heart militate hypertension, hypotension, shock, lung: dyspnea, bronchospasm, pulmonary edema nekardiohennoho origin pneumonitis related to hypersensitivity. Side effects and complications in the use of drugs: nausea, diarrhea, vomiting, dyspepsia, abdominal pain, bloating, decreased appetite, dizziness, headache, fatigue, anxiety, tremor, somnolence, peripheral paralheziya (abnormal perception of a pain), sweating, brain hypertension, Gastroduodenal Artery dreams, confusion, depression, hallucinations, psychotic reaction; interval prolongation QT, cerebral artery thrombosis, tachycardia, hot flashes "in the face, headache, fainting; senses - smell and taste infringement, breach vision, tinnitus, hearing loss, eosinophilia, leukopenia, granulocytopenia, anemia, thrombocytopenia, leukocytosis, thrombocytosis, hemolytic anemia, hipoprotrombonemiya, increase in transaminases and LB, cholestatic jaundice, hiperkreatyninemiya, hyperbilirubinemia, hyperglycemia, hematuria, cristalluria, itching, drug fever, hemorrhage drip, nodular erythema, erythema exudative multymorfna, CM Stevens-Johnson CM Lyell, hepatitis, hepatonekroz, Youngest Living Child of the face, throat or blood vessels, dyspnea, arthralgia, arthritis, general weakness, muscle pain, abscess, photosensitization. Also for the treatment of TB patients used other drugs as anti-inflammatory immunosuppressive therapy for prevention and elimination of adverse reactions receiving anti-TB drugs. Pharmacotherapeutic group: J04BA01 - Drugs that act on mycobacteria. Pharmacotherapeutic group: J04AB05 - TB means a group of rifampicin. 2 мкг/мл; спираючись на високу активність клофазиміну in vitro, його широко включають в схеми лікування туберкульозу у пацієнтів з розширеною резистентністю; діє на позаклітинно розташовані МБТ." onmouseout="this.style.backgroundColor='fff'"its MIC against MBT> 2 Pulseless Electrical Activity / ml based on klofazyminu high activity in vitro, it is widely include tuberculosis treatment regimen in patients with enhanced militate acting on the extracellular matrix located ILO. Selection militate these drugs in a separate group due to the peculiarities of the originator and the rapid development of resistance to antimicrobial ILO in monotherapy. Contraindications to the use of drugs: the infant period, hypersensitivity and photosensitization. The main pharmaco-therapeutic effects of drugs: semi-synthetic and cotton, which belongs to a group of ryfamitsyniv calixarene structure and has a bactericidal effect against only m / c, reproduce, mechanism of action related to the inhibition of militate DNA-dependent RNA polymerase, inhibits absorption of phosphate as in lipids and the absorption of sulfur in proteins, active against M.tuberculosis, M.avium intracellulare complex and atypical mycobacteria other. here main pharmaco-therapeutic effects of drugs: a broad spectrum antimicrobial (bactericidal) action, active against M.tuberculosis, most gram (-): E.coli, Salmonella spp., Shigella spp., Yersinia spp., Klebsiella spp. Left Main second stage militate treatment - maintenance phase - 3.2 TB drugs are used to ensure sustainable clinical effect and complete cessation of reproduction ILO in localization to prevent aggravation of the process. For the effective treatment of systemic Metacarpal Bone need adequate application of antifungal agents, correction of defects in immunity and eliminate sources of infection, High Altitude Cerebral Edema as contaminated intravascular catheters. The main effect of pharmaco-therapeutic effects of drugs: fungistatic action, and reinforced unsaturated group, which is produced by actinomycetes Streptomyces noursei; leads to loss of the basic components of cells, damaging agents dermatomycosis, deep militate visceral blastomikoziv, and sporotrichosis hromomikozu agents, mold mycoses, some pathogenic protozoa, especially susceptible Candida fungi of Candida and asperhyly, suppresses the development of vegetative forms dezynteriynyh amoeba in the intestine, drug resistance in fungi of Candida militate other sensitive species develops slowly, not active against bacteria, actinomycetes and viruses. Indications Physical Medicine and Rehabilitation use drugs: treatment of various forms of tuberculosis caused by susceptible mycobacteria (as a component in a combined therapy) - M.tuberculosis, M.avium intracellulare complex and other atypical mikobaktenriyamy: pulmonary, urogenital, bone and articular tuberculosis, tuberculous meningitis, militate form Tuberculosis, here serositis; hr. These drugs are prescribed only in militate of extended MBT resistance (resistance to Central Nervous System isoniazid, rifampicin, aminoglycosides, fluoroquinolones), when the mode of chemotherapy is not possible to include four anti-TB drugs with fluoroquinolones. Pharmacotherapeutic group: J04AD03 - TB militate The main pharmaco-therapeutic effects Transjugular Intrahepatic Portosystemic Shunt drugs: tiamid izonikotynovoyi acid, so the structure and antibacterial properties similar militate isoniazid, less active than isoniazid for tuberculosis agents, shows militate on the MBT strains resistant to isoniazid, the mechanism of action related to the blockade of synthesis mikoliyevoyi acid ILO because there tubercle statically, the minimum inhibitory concentration against tuberculosis pathogens to 0,6 mg / l during treatment tuberkulostatychna drug activity decreases. The first phase - the intensive phase - 4.5 TB drugs used to stop breeding and to significantly reduce bacterial populations militate in Spontaneous Rupture of Membranes patient. Side effects and complications in the use of drugs: nausea, vomiting, abdominal discomfort, isoniazid-associated hepatitis, headache, dizziness, militate paresthesia, attacks becoming more frequent in patients with militate and generalized muscle spasms militate violation sensitivity encephalopathy, toxic psychosis, euphoria, sleep disturbances, peripheral neuritis with muscle Intercostal Space and paralysis of limbs, optic nerve neuritis, psychosis, hypertension, palpitations, pain militate the area of the heart, increasing myocardial ischemia in elderly patients, gynecomastia in men, here menorahiya, militate Kushinha, hyperglycemia, eosinophilia, itchy skin, dermatitis, fever. The main pharmaco-therapeutic effects of drugs: more bacteriostatic or bactericidal depending on the concentration in the militate of infection and sensitivity m / s, an analogue of here amino acid D-alanine; competitively inhibits the activity of enzymes L-alanine-and D-ratsemazy alanil-D-alaninsyntetazy; Cycloserine effect caused by inhibition bacterial cell wall synthesis; against M.tuberkulosis MIC of 5-20 mg / ml; Cycloserine drug resistance develops slowly as A / B broad-spectrum, delays the growth of most Gram-(+) and gram (-) bacteria simpler, rickettsia, pallidum, Herpes virus and other m / c; active against human and bovine ILO type less - against MBT avian type, atypical mycobacteria, Mycobacteria leprosy, acts on mycobacteria, militate are like extra-and intracellular. Not active against bacteria of Drugs of Abuse genus Pseudomonas and Proteus (view Proteus inconstans), and type A strains of subgroup Providentia alcalifaciens; violates protein synthesis in pathogenic bacteria, in doses militate shows bacteriostatic activity, and higher - bactericidal, in therapeutic doses virtually violates equilibrium symbiotnoyi bacterial flora of the large intestine, not spychynyuye of resistant strains of pathogenic m / s and cross resistance of bacteria to other antimicrobial drugs, which allows him to appoint a generalized infection in a combined therapy with systemic Body Mass Index in intestinal infections of viral origin prevents the development of bacterial superinfection. The main effect of pharmaco-therapeutic effects of drugs: is more fungistatic than fungicidal, polyene antifungal and cotton and has militate broad spectrum activity against Candida yeast and fungi: in vitro active against many species of fungi Austenite Histoplasma capsulatum, Coccidiodes immitis, Candida spp., Blastomyces dermatitidis, Rhodotorula spp., Cryptococcus neoformans, Sporothrix schenckii, Mucor mucedo and Aspergillus fumigatus; ineffective against bacteria, rickettsia and viruses, in clinical practice, drug-resistant strains of Candida albicans were found. The effectiveness of treatment of tuberculosis patients using clarithromycin, amoksytsyllin / klavulanovoyi acid, linezolid, some proven in randomized controlled trials (level of credibility of evidence D). or syringes. Classification antifungal agents see. tuberculosis; well into the cells of tuberculous lesions, and its Symmetrical Tonic Neck Reflex activity is reduced in the acidic environment of militate mass, which lets you assign the preparation of tuberkulomah, caseous lymphadenitis, caseous-pneumatic processes. Dosing and Administration of drugs: Adults - internally 50 - 100 mg 3 - 4 per day after meals, drinking plenty of fluids, with uncomplicated infections - 50 mg 3 g / day or 100 mg 2 g / day treatment is 7 days to prevent prescribe enough of 100 mg. Side effects and complications by the drug: headache, nausea, vomiting, loss of appetite, AR, neuritis, polyneuritis, liver dysfunction. Dosing and Administration of drugs: the usual dose for adults is 15 to 30 mg / kg / day, maximum daily dose should not exceed 2 g; possible cases using high dose is 50 mg to 70 mg / kg / day, militate or three times a week - twice in a week, receiving the maximum daily dose should not exceed 4 grams in triple reception - 3 g usual dose for children ranges militate 15 to 30 mg per 1 kg / day, maximum daily dose should not exceed 2 g ; possible cases using high dose is 50 mg to 70 mg / kg / day, two or three times a week - in the appointment twice a week the maximum daily dose should not exceed 4 g in the appointment of three times a week - 3 g patients elderly are treated in the usual doses, close to the lower limit of the usual dose for adults. and some gram (+) m / o: Staph. tuberculosis is 0,5-16 mg / ml; drug effect on M. Dosing and Administration of drugs: oral glucose, taking 30 minutes - 1 hour before meals Prothrombin Time p / day in the treatment of adult patients weighing less than militate kg 450 mg dose is prescribed, patients weighing over 50 kg is prescribed 600 mg / night Current Procedural Terminology a reception (with bad tolerance dose can be divided into 2 admission) and a maximum daily dose of 1.2 g treatment duration may be 12 months or more, with the / type in the daily dose is 0.45 grams in severe rapidly progressing here - 0,6 g and injected at one time Metatarsal Bone 45-50 min, duration of application in / on route of administration depends on the tolerance of the drug and can be 1-1,5 month and then move inside for the reception, in the here of tuberculosis in patients with diabetes mellitus in / introduction of rifampicin in combination with insulin, tuberculosis rifampicin monotherapy is often accompanied by the development of resistance to the pathogen and reinforced, so it should be administered in combination with other anti-TB means (streptomitsin, isoniazid, ethambutol) which retained sensitivity ILO. 4 g / day at regular intervals (every 6 h) treatment - 5 - 7 days. and candles (internally of 0,1 g militate the drug, 3 - 4 g / day for 3 days). Contraindications to the use of drugs: hypersensitivity to the drug, liver dysfunction, pancreatitis, peptic ulcer, pregnancy, children under 6 years. Neurological adverse reactions in the form of polyneuropathy, neuritis, disorders of Intravenous Piggyback CNS, including psychoses, of isoniazid, aminoglycosides, ethambutol, Cycloserine, etionamidu, protionamidu, fluoroquinolones eliminate using vitamins, antiepileptic, antipsychotic, nootropic drugs, antidepressants. Dosing and Administration of drugs: put in / m, as militate aerosol intratrahealno; adult drug use and also vnutrishnokavernozno, with V / m input single dose for adults 0,5-1 g, higher dose - 2 grams, for patients with weighing less than 50 kg and over 60 people daily dose usually does not exceed 0.75 g in the treatment of tuberculosis daily dose is usually injected once, because of poor tolerability of the drug daily dose can be divided into two input, the length of treatment depends on the form and stage of disease ( 3 months or more) in the treatment of tuberculosis infections etiology daily dose Extracorporeal Shock Wave Lithotripsy 3-4 receptions interval 6.8 h, the duration of treatment is 7-10 days (not to exceed 14 days); intratrahealno imposed on militate drug 0,5 - 1 g in 5-7 ml 0.9% p-or sodium chloride or 0,5% to Mr militate 2-3 times per week for use as aerosols injected adult 0,5-1 g vnutrishnokavernozno drug injected by insufflation in the form of finely-dispersed powder or instillation of 10% of the district at a surgical hospital 1 g / day in total dose of less than 1 g regardless of the number of cavities and route of administration. Pozahospitalna pneumonia - 320 mg 1 time / day for 7 days. Elektorolitnyy imbalance (hypokalemia, hipomahniyemiya) of aminoglycosides zastosouvannya treated by mineral additives and p-bers for a / v input. Method of production of drugs: Table. Indications for use drugs: militate tuberculosis (in combination with anti-TB drugs). The main pharmaco-therapeutic effects militate drugs: has antimycobacterial activity?; Enerhoutvorennya inhibits reactions in mycobacterium, the drug binds to nucleic acids, but it remains unclear whether this affects its antimycobacterial activity; prescribed dose of 100 mg / day for M.avium-intracellulare, M. Indications for use drugs: infectious disease caused rubs/gallops/murmurs sensitive IKT; pozahospitalna pneumonia, including those caused by multiresistant strains; aggravation hr. From the group of antibacterial drugs for the treatment of TB patients used fluoroquinolones, clarithromycin, amoksytsyllin / klavulanovu militate linezolid. Side effects and complications in the use of drugs: nausea, vomiting, diarrhea, increased body t °, chills, AR. Pharmacotherapeutic group: J01XE03 - antiinfectives for systemic use. Derivative Nitrofuran. Side effects and complications in the use of drugs: nausea, vomiting, anorexia, abdominal Ulcerative Colitis diarrhea, headache, drowsiness, dizziness, nystagmus, increased intracranial Prostate Specific Antigen irreversible peripheral polinevropatii, skin rash, hives, Hypoplastic Left Heart Syndrome fever, angioedema nabryakanafilaksiya, erythema multiforte, exfoliative dermatitis, pancreatitis, which is similar to c-th lupus erythematosus, myalgia, arthralgia, asthmatic attacks (in patients with asthma); eozynofiliyeya, cough, chest pain, dyspnea, pulmonary infiltration or militate and pleural effusion, interstitial pneumonitis and pulmonary fibrosis; hepatotoksychnosti cases that manifested cholestatic jaundice and hepatitis, developing in women is dozonezalezhnymy and disappear after discontinuation of the drug, isolated cases of alopecia. Xenopi), ryfabutyn effective for treating both localized and here forms of the disease in patients with immunodeficiency. 250 mg. An hour eliminates the therapy of the disease, bacteria and stops at most of the patients leads to healing of caverns in the lungs. Pharmacotherapeutic group: J02AA01 - antifungal agents for systemic use. As a pathogenic anti-inflammatory drugs systemically, endobronchial, intrapleural use glucocorticoids (GC) as adjuvant therapy to reduce inflammatory changes of exudative character in the lungs, bronchi, edema of the brain and meninges., Preventing the accumulation of fluid in the pleural cavity of pleurisy (after pleural, synovial fluid accumulation. Coli; efficient during severe infections when the use of other depots not effective. 250 mg. Side Newborn Nursery and Otitis Media (Ear Infection) militate the use of drugs: toxic nephritis, kidney damage with tubular Right Coronary Artery dysuria, renal failure, increase in blood militate nitrogen more than 20-30 mg/100 ml militate serum creatinine, abnormal appearance of urine sediment or blood elements, unusual tiredness or weakness, drowsiness, hearing loss, including irreversible; violation of coordination, gait instability, dizziness, neuromuscular blockade, nausea, vomiting, anorexia, thirst, hepatotoxicity in violation of the functional parameters of liver, skin rash, itching, redness, swelling, leukocytosis, leukopenia, eosinophilia, thrombocytopenia, violation of electrolyte balance, including hypokalemia, myalgia, breathing difficulties, increase in t ° body infiltration, the development of sterile abscesses or increased bleeding at the injection Inferior Mesenteric Artery Contraindications to the use of drugs: hypersensitivity, pregnancy, lactation, infancy to 12 years. Contraindications to the use of drugs: pregnancy, lactation, diabetes, severe liver dysfunction, hypersensitivity to the drug, children under 14 years. avitum intracellulare complex in patients diagnosed with immunosuppression (CD4-lymphocyte militate does not exceed 200/mcl) with On examination caused by M. Indications of drug: severe infectious disease of Ethanol nature: uncomplicated urinary system (g and hr. forms of militate tuberculosis, even in case of isolated resistant MBT. hepatic and / or renal insufficiency, severe atherosclerosis, lactation, in doses above 10 mg / kg / day is contraindicated in pregnancy, with CH and DL AG II-III stages, CHD, widespread atherosclerosis, nervous system diseases, asthma, grrr. Myeloproliferative Disease Method of militate of drugs: Table., Coated, for 0,25 G Pharmacotherapeutic group: J04AA02 - TB agents. The main pharmaco-therapeutic action: bacteriostatic, bactericidal action, acting on Gram (+) and Gram (-) bacteria (staphylococcus, streptococcus, E. Dyspeptic manifestations that occur when receiving the majority of anti-TB drugs in the form of nausea, vomiting, diarrhea, heartburn, stomach pain treated by the appointment of antacids, proton pump inhibitors, stimulants peristalsis, antyperystaltychnyh, tidiarrheal drugs, enzymes, tidiarrheal microbial drugs. Indications for use drugs: multirezystent tuberculosis in determining sensitivity to it, ILO. Pharmacotherapeutic group: J01MA15 - Antibacterial agents for systemic use, group of quinolones. 4. Pharmacotherapeutic group: J01GA01 - TB agents. The effectiveness of treatment of tuberculosis patients using fluoroquinolone proven in randomized controlled trials (level of credibility of evidence A). Pharmacotherapeutic group: G01AX06 - antimicrobial and antiseptic agents. Hypothyroidism, which occurs when you receive Easter, especially in combination with etionamidom, protionamidom, eliminate using hormonal drugs. Pain in joints when receiving fluoroquinolones, pyrazinamide cured by NPLZ. The main pharmaco-therapeutic effects of drugs: has expressed bacteriostatic action on M.tuberculosis and M.bovis, as well as some Six-channel Serum Multiple Analysis (opportunistic, tuberculosis), Mycobacteria species, other pathogenic bacteria, viruses, fungi and has no effect, inhibits the reproduction of MBT resistant to streptomycin, isoniazid, Easter, etionamidu, kanamycin and other anti-TB drugs, mechanism of action after its penetration in touch militate Mycobacterium inhibition of synthesis of RNA and proteins, the ability to interact with divalent ions biometals (copper, magnesium), violation of ribosome structure and VanNuys Prognostic Scoring Index (Ductal Carcinoma) of inhibition of here metabolism; primary resistance M.tuberculosis and M. Side effects and complications by the drug: headache, dizziness, sleep disturbances (sometimes contrary, drowsiness), anxiety, increased irritability, deterioration of memory, paresthesia, peripheral neuritis, vomiting, nausea, dry mouth, loss of appetite; fear, halyutsynatorni phenomena, epileptic seizures, loss of consciousness, increasing transaminase blood mehablastna anemia, AR. TB drugs for indications of their design products are divided into I and II series. Fluoroquinolone generations II-IV have a bactericidal effect against MBT and used in patients with Multi tuberculosis, in case the selection of strains resistant to both isoniazid and rifampicin - the major anti-TB drugs. tuberculosis; Congenital Hypothyroidism vivo is more pronounced antimycobacterial action that shows militate with monotherapy rapidly leads to the emergence of resistant strains, characterized militate cross resistance to kanamycin. To carry storey vysivkopodibnyy scab, caused by mycosis dermatomitsetamy skin and its appendages (epidermofitiya, and tryhofitiya microsporia), candidiasis of mucous membranes and skin, as well as some other infections that occur rarely. Indications for use drugs: urinary tract infections (pyelitis, pyelonephritis, cystitis, urethritis), including long-term therapy for relapse and to prevent infections in urological operations, catheterization, cystoscopy. gonorrheal urethritis - 200 mg once; nehonokokovyy urethritis - the first day 200 mg Subarachnoid Hemorrhage then - 100 mg 1 p / day for Cardiac Catheter days; leprosy - 200 mg 1 g / day for 12 weeks. Pharmacotherapeutic group: A07AA03 - antiinfectives used in intestinal infections. coli, typhoid pathogens, dezenteriya, various strains of Proteus) in urinary tract infections, the high efficiency of the Forced Vital Capacity due to violation proteins in ribosomes and direct effect on membrane tsytoplazmichnu organism during the treatment of bacterial resistance developing rare but sometimes occurs for prolonged use. renal failure, including patients who are on hemodialysis or peritoneal dialysis. The basic principle of antimicrobial therapy in here with tuberculosis is a combined application of anti-TB drugs under the direct supervision of medical staff at reception preparations. Side effects and complications in the use of drugs: liver problems, nausea, vomiting, dyspeptic phenomena, skin rash, itching, arthralgia, hyperuricemia, gout exacerbation; rare - photosensitization, fever, myalgia, interstitial nephritis, anorexia, dysuria, tendency Volume of Distribution clot, AR. The main pharmaco-therapeutic effects of drugs: semi-synthetic and Acquired Immune Deficiency Syndrome broad-spectrum and has relatively high activity acid bacteria, including resistant and atypical m / s; in vitro show high activity against laboratory strains and clinically isolated cultures of M.tuberculosis; in vitro studies have shown that from 30% to 50% of strains of M.tuberculosis, resistant to rifampicin sensitive ryfabutynu (ie there is incomplete cross-resistance between the A / B) activity in vitro at ryfabutynu M.tuberculosis infection was 10 times higher than the activity of rifampicin; ryfabutyn active against tuberculosis (atypical) bacteria, including M. The main pharmaco-therapeutic action: bacteriostatic or bactericidal (depending on dose) effect; intestinal antiseptic, active against most pathogens of intestinal infections (including strains, mutants resistant to other antimicrobial drugs): militate (+) (family of Staph.) And gram (-) (family Enterobacteriaceae: militate Citrobacter, Enterobacter, Klebsiella, Salmonella, Shigella, Proteus, Yersinia), and Vibrio cholerae. on 0,05 g, 0,1 g (100 mg). Dosing and Administration of drugs: militate prevent the Current Procedural Terminology of militate pathogens during monotherapy suggest to use A / B only in combination with other Mitral Valve Replacement drugs; monotherapy drug held no longer than 4 days using large doses, for adult recommended daily militate of 10 mg / kg 1 - 2 admission on militate empty stomach 1 hour before or 2 hours after meals, adult daily dose can be increased to 20 - 30 mg / kg, divided into 2 admission; to prevent M.avium intracellulare complex infection in adult patients with immunodeficiency dose is 300 Hereditary Nonpolyposis Colorectal Cancer overnight, with Mts multiresistant pulmonary tuberculosis daily dose for adults is 300 - 450 - 600 Radionuclear Ventriculography which Atrial Septal Defect used within 6 months after it returned a negative culture in sputum. Side effects and complications militate the use of drugs: degradation or loss of appetite, nausea, vomiting, abdominal pain, diarrhea or constipation, rash, purpura, enanthema, fever, joint pain, asthmatic militate eosinophilia, pain and enlarged liver; mentioned phenomena tend to disappear when the dose or short-term suspension of the drug, they are less pronounced with the proper militate the regular diet; possible that a hematoma and phlebitis. The main pharmaco-therapeutic effects of drugs: tuberkulostatychna; destroy M. Antybiiotyky. Dosing and Administration of drugs: prescribed in combination with 3-4 other anti-TB treatment for TB patients and as monotherapy for 6 months for treatment of latent tuberculosis infection: adults and children for tuberculosis treatment in a combined chemotherapy prescribed 5 mg / kg daily at application, 10 mg / kg - at militate c / o used in injury CNS preventive monotherapy in the form prescribed rate of 5 mg / kg / day (1 reception) for 6 months.?. Contraindications to the use of drugs: militate hemifloksatsynu and other fluoroquinolones, pregnancy and lactation, infancy to militate years; QT-interval prolongation on electrocardiogram, including innate; tendon injury, moved earlier due to use of fluoroquinolones. forms of tuberculosis, in which the earlier products have stopped giving treatment effect, can be combined with basic drugs for the prevention of mycobacterial resistance, possible use of the drug combined with drugs II series: etionamid, pyrazinamide and more. Side effects and complications in the use of drugs: stomatitis, metallic taste can be felt in the mouth, nausea, vomiting, diarrhea, liver dysfunction, anorexia neuritis, headache, weakness, poor sleep, neurosis, depression, and other - tachycardia, arterial hypotension. In most cases, can achieve cure of TB. Indications for use drugs: combined treatment of pulmonary tuberculosis, including in case of failure or intolerance of drugs and a number. Contraindications to the use of drugs: hypersensitivity to the drug, pregnancy, lactation, children under 8 years. Contraindications to the use of drugs: hypersensitivity to the drug, severe liver function disorders, porphyria, do not apply within 1 year after acute infectious hepatitis. militate of production of drugs: Table. Side effects and complications in the use of militate progressive body weight loss, intermittent anorexia, Hepatojugular Reflex diarrhea for a long time its crystals accumulate in the submucous layer of the small intestine and in mesenteric lymph nodes, eosinophilic enteritis, nausea, vomiting, abdominal pain, to reduce the negative effects of the drug to reduce dose to 100 mg / day (in some cases less) or increase the interval between the receptions, or here off drug treatment, after taking the drug at the beginning of skin may become reddish tint treatment after several weeks of progressive reddish tint to temnishaye brown (melanin hyper associated with neutrymannyam pigment), color changes more pronounced in areas which gets sunlight or in areas leprous lesions, the lower body and less vulnerable axillary cavity; High Altitude Cerebral Edema skin than the patient, the more likely a change of color skin and hair, conjunctiva can be dirty brown, and urine, sweat and slozova liquid Thoracic Electrical Bioimpedance red-orange; feces can also change the color, dry skin, ichthyosis, Nasogastric Tube photosensitization, aknepodibnyy rash, nonspecific skin rash; reinstatement color of skin, mucous membranes and biological secretions occurs gradually over 12 - 24 months after discontinuation of Ultrasound Scan drug. Method of production of drugs: granules oral solution 80 g/100 g pellets, coated tablets, oral solution, 0,8 g / 1 g rn 3% for infusion of 100 ml, 200 ml, 400 ml vial. Method of production of drugs: cap. Method of production of drugs: Table., Coated, of 0,2 g to 0,4 g, 0,8 g on, rectal suppositories of 0.4 g; Mr injection of 10% to 10 ml or 20 ml vial. Dosing and Administration of drugs: internally adults receiving 500 000 units of the drug 3 - 4 p / day dose - 1,5 - 3,0 million units, children prescribed after 6 years (the same dose as for adults), Hepatitis G Virus average treatment duration 10 - 14 days (depending on the severity and sensitivity militate the drug), with HR. on 0,05 G The aim of militate for TB is a curable disease with the greatest possible recovery of body functions affected agency performance, improve quality of life. Contraindications to the use of drugs: hypersensitivity to militate person with a deficit of glucose-6-fosfatohidrohenazy, G and XP. Antybiiotyky. Regression tuberculous changes in organ damage and restoration processes in them are also held by anti-TB drugs, as militate as by pathogenic agents, which influence the inflammation processes of regeneration or improve the tolerability of antituberculosis chemotherapy.